Thursday 29 January 2015

Ken Sikaris: Blood Panel for cardiovascular risk January 2015

The Ken Sikaris lectures

Dr Ken Sikaris is a chemical pathologist at Melbourne Pathology. He is a Senior Fellow of St Vincent's Clinical School and a Clinical Associate in Biochemistry at the University of Melbourne.

A graduate of the University of Melbourne, Dr Sikaris trained at the Royal Melbourne, Queen Victoria, and Prince Henry's Heidelberg Repatriation Hospitals. He obtained fellowships from the Royal College of Pathologists of Australasia and the Australasian Association of Clinical Biochemists in 1992 and 1997 respectively. Dr Sikaris was Director of Chemical Pathology at St Vincent's Hospital in Melbourne between 1993 and 1996. A NATA-accredited laboratory assessor, Dr Sikaris specialises in Prostate Specific Antigen, cholesterol and quality assurance and is currently chair of the International Federation of Clinical Chemistry Committee on Analytical Quality. His expertise is highly sought and he has presented extensively at national and international symposiums. Dr Sikaris is a Senior Fellow of St Vincent's Clinical School and a Clinical Associate in Biochemistry at the University of Melbourne. He joined Melbourne Pathology in 2003


NZ April 2014

St Kilda Oct 2014 introduction





St Kilda Jan 2015 LCHF














  1. Hb1Ac  <5.1
  2. Trig  <1  
  3. ALT
  4. Troponin

Sunday 18 January 2015

Vegan for the 20 something

Ella story



 

Pea and Spinach Pesto Pasta

pasta2blog
This dish has been my saviour throughout January – I mean who could say no to a bowl of creamy pine nut and basil pesto tossed with peas, brown rice pasta, wilted spinach and then finished with lots of lemon and black pepper?! I’ve made it a few too many times but still can’t get enough of it. It’s the simplest thing to throw together, it really does just take ten minutes to make and doesn’t require any fancy ingredients at all. I love the simplicity of it though, I think that’s why I keep coming back to it, as I know that no matter how tired or hungry I am, I can whip it up quickly and feel so nourished and satisfied afterwards. All the ingredients are so delicious too and they come together perfectly, you’re going to love it!
pasta4blogpastablogpasta6blogServes 4
For the pesto
– 2/3 of a cup of pine nuts, 100g
– 2/3 of a cup of olive oil, 200ml
– a big handful of fresh basil, 30g
– 2 cloves of garlic
– 2 lemons
– salt
For the pasta
– pasta, I use brown rice pasta
– half a bag of frozen peas, 300g
– a bag of spinach, 200g
– 1 lemon
pasta1blog
Tear all the basil leaves off their stems, juice the lemons and peel the garlic. Then place all these with the other pesto ingredients into a food processor and blend until smooth and creamy. Leave this to one side while you make the pasta.
Place the pasta and the peas into a saucepan with boiling water and cook until the pasta is ready. Drain the pasta and the peas, then place them back into the saucepan along with the pesto and spinach. Cook everything together on a low heat until the pesto is warm and the spinach has wilted. Finally squeeze the juice of the last lemon over the pasta, sprinkle it with salt and add lots of black pepper before serving and enjoy!

Decision Making during the Day

Sunday 18 January 2015


 Our brains are busier than ever before. We’re assaulted with facts, pseudo facts, jibber-jabber, and rumour, all posing as information. Trying to figure out what you need to know and what you can ignore is exhausting. At the same time, we are all doing more. Thirty years ago, travel agents made our airline and rail reservations, salespeople helped us find what we were looking for in shops, and professional typists or secretaries helped busy people with their correspondence. Now we do most of those things ourselves. We are doing the jobs of 10 different people while still trying to keep up with our lives, our children and parents, our friends, our careers, our hobbies, and our favourite TV shows.
Our smartphones have become Swiss army knife–like appliances that include a dictionary, calculator, web browser, email, Game Boy, appointment calendar, voice recorder, guitar tuner, weather forecaster, GPS, texter, tweeter, Facebook updater, and flashlight. They’re more powerful and do more things than the most advanced computer at IBM corporate headquarters 30 years ago. And we use them all the time, part of a 21st-century mania for cramming everything we do into every single spare moment of downtime. We text while we’re walking across the street, catch up on email while standing in a queue – and while having lunch with friends, we surreptitiously check to see what our other friends are doing. At the kitchen counter, cosy and secure in our domicile, we write our shopping lists on smartphones while we are listening to that wonderfully informative podcast on urban beekeeping.
But there’s a fly in the ointment. Although we think we’re doing several things at once, multitasking, this is a powerful and diabolical illusion. Earl Miller, a neuroscientist at MIT and one of the world experts on divided attention, says that our brains are “not wired to multitask well… When people think they’re multitasking, they’re actually just switching from one task to another very rapidly. And every time they do, there’s a cognitive cost in doing so.” So we’re not actually keeping a lot of balls in the air like an expert juggler; we’re more like a bad amateur plate spinner, frantically switching from one task to another, ignoring the one that is not right in front of us but worried it will come crashing down any minute. Even though we think we’re getting a lot done, ironically, multitasking makes us demonstrably less efficient.
Multitasking has been found to increase the production of the stress hormone cortisol as well as the fight-or-flight hormone adrenaline, which can overstimulate your brain and cause mental fog or scrambled thinking. Multitasking creates a dopamine-addiction feedback loop, effectively rewarding the brain for losing focus and for constantly searching for external stimulation. To make matters worse, the prefrontal cortex has a novelty bias, meaning that its attention can be easily hijacked by something new – the proverbial shiny objects we use to entice infants, puppies, and kittens. The irony here for those of us who are trying to focus amid competing activities is clear: the very brain region we need to rely on for staying on task is easily distracted. We answer the phone, look up something on the internet, check our email, send an SMS, and each of these things tweaks the novelty- seeking, reward-seeking centres of the brain, causing a burst of endogenous opioids (no wonder it feels so good!), all to the detriment of our staying on task. It is the ultimate empty-caloried brain candy. Instead of reaping the big rewards that come from sustained, focused effort, we instead reap empty rewards from completing a thousand little sugar-coated tasks.
In the old days, if the phone rang and we were busy, we either didn’t answer or we turned the ringer off. When all phones were wired to a wall, there was no expectation of being able to reach us at all times – one might have gone out for a walk or been between places – and so if someone couldn’t reach you (or you didn’t feel like being reached), it was considered normal. Now more people have mobile phones than have toilets. This has created an implicit expectation that you should be able to reach someone when it is convenient for you, regardless of whether it is convenient for them. This expectation is so ingrained that people in meetings routinely answer their mobile phones to say, “I’m sorry, I can’t talk now, I’m in a meeting.” Just a decade or two ago, those same people would have let a landline on their desk go unanswered during a meeting, so different were the expectations for reachability.
Just having the opportunity to multitask is detrimental to cognitive performance. Glenn Wilson, former visiting professor of psychology at Gresham College, London, calls it info-mania. His research found that being in a situation where you are trying to concentrate on a task, and an email is sitting unread in your inbox, can reduce your effective IQ by 10 points. And although people ascribe many benefits to marijuana, including enhanced creativity and reduced pain and stress, it is well documented that its chief ingredient, cannabinol, activates dedicated cannabinol receptors in the brain and interferes profoundly with memory and with our ability to concentrate on several things at once. Wilson showed that the cognitive losses from multitasking are even greater than the cognitive losses from pot‑smoking.
Russ Poldrack, a neuroscientist at Stanford, found that learning information while multitasking causes the new information to go to the wrong part of the brain. If students study and watch TV at the same time, for example, the information from their schoolwork goes into the striatum, a region specialised for storing new procedures and skills, not facts and ideas. Without the distraction of TV, the information goes into the hippocampus, where it is organised and categorised in a variety of ways, making it easier to retrieve. MIT’s Earl Miller adds, “People can’t do [multitasking] very well, and when they say they can, they’re deluding themselves.” And it turns out the brain is very good at this deluding business.
Brain
Pinterest
‘Asking the brain to shift attention from one activity to another causes the prefrontal cortex and striatum to burn up oxygenated glucose, the same fuel they need to stay on task.’ Photograph: Alamy
Then there are the metabolic costs that I wrote about earlier. Asking the brain to shift attention from one activity to another causes the prefrontal cortex and striatum to burn up oxygenated glucose, the same fuel they need to stay on task. And the kind of rapid, continual shifting we do with multitasking causes the brain to burn through fuel so quickly that we feel exhausted and disoriented after even a short time. We’ve literally depleted the nutrients in our brain. This leads to compromises in both cognitive and physical performance. Among other things, repeated task switching leads to anxiety, which raises levels of the stress hormone cortisol in the brain, which in turn can lead to aggressive and impulsive behaviour. By contrast, staying on task is controlled by the anterior cingulate and the striatum, and once we engage the central executive mode, staying in that state uses less energy than multitasking and actually reduces the brain’s need for glucose.
To make matters worse, lots of multitasking requires decision-making: Do I answer this text message or ignore it? How do I respond to this? How do I file this email? Do I continue what I’m working on now or take a break? It turns out that decision-making is also very hard on your neural resources and that little decisions appear to take up as much energy as big ones. One of the first things we lose is impulse control. This rapidly spirals into a depleted state in which, after making lots of insignificant decisions, we can end up making truly bad decisions about something important. Why would anyone want to add to their daily weight of information processing by trying to multitask?
In discussing information overload with Fortune 500 leaders, top scientists, writers, students, and small business owners, email comes up again and again as a problem. It’s not a philosophical objection to email itself, it’s the mind-numbing number of emails that come in. When the 10-year-old son of my neuroscience colleague Jeff Mogil (head of the Pain Genetics lab at McGill University) was asked what his father does for a living, he responded, “He answers emails.” Jeff admitted after some thought that it’s not so far from the truth. Workers in government, the arts, and industry report that the sheer volume of email they receive is overwhelming, taking a huge bite out of their day. We feel obliged to answer our emails, but it seems impossible to do so and get anything else done.
Before email, if you wanted to write to someone, you had to invest some effort in it. You’d sit down with pen and paper, or at a typewriter, and carefully compose a message. There wasn’t anything about the medium that lent itself to dashing off quick notes without giving them much thought, partly because of the ritual involved, and the time it took to write a note, find and address an envelope, add postage, and take the letter to a mailbox. Because the very act of writing a note or letter to someone took this many steps, and was spread out over time, we didn’t go to the trouble unless we had something important to say. Because of email’s immediacy, most of us give little thought to typing up any little thing that pops in our heads and hitting the send button. And email doesn’t cost anything.
Sure, there’s the money you paid for your computer and your internet connection, but there is no incremental cost to sending one more email. Compare this with paper letters. Each one incurred the price of the envelope and the postage stamp, and although this doesn’t represent a lot of money, these were in limited supply – if you ran out of them, you’d have to make a special trip to the stationery store and the post office to buy more, so you didn’t use them frivolously. The sheer ease of sending emails has led to a change in manners, a tendency to be less polite about what we ask of others. Many professionals tell a similar story. One said, “A large proportion of emails I receive are from people I barely know asking me to do something for them that is outside what would normally be considered the scope of my work or my relationship with them. Email somehow apparently makes it OK to ask for things they would never ask by phone, in person, or in snail mail.”
There are also important differences between snail mail and email on the receiving end. In the old days, the only mail we got came once a day, which effectively created a cordoned-off section of your day to collect it from the mailbox and sort it. Most importantly, because it took a few days to arrive, there was no expectation that you would act on it immediately. If you were engaged in another activity, you’d simply let the mail sit in the box outside or on your desk until you were ready to deal with it. Now email arrives continuously, and most emails demand some sort of action: Click on this link to see a video of a baby panda, or answer this query from a co-worker, or make plans for lunch with a friend, or delete this email as spam. All this activity gives us a sense that we’re getting things done – and in some cases we are. But we are sacrificing efficiency and deep concentration when we interrupt our priority activities with email.
Until recently, each of the many different modes of communication we used signalled its relevance, importance, and intent. If a loved one communicated with you via a poem or a song, even before the message was apparent, you had a reason to assume something about the nature of the content and its emotional value. If that same loved one communicated instead via a summons, delivered by an officer of the court, you would have expected a different message before even reading the document. Similarly, phone calls were typically used to transact different business from that of telegrams or business letters. The medium was a clue to the message. All of that has changed with email, and this is one of its overlooked disadvantages – because it is used for everything. In the old days, you might sort all of your postal mail into two piles, roughly corresponding to personal letters and bills. If you were a corporate manager with a busy schedule, you might similarly sort your telephone messages for callbacks. But emails are used for all of life’s messages. We compulsively check our email in part because we don’t know whether the next message will be for leisure/amusement, an overdue bill, a “to do”, a query… something you can do now, later, something life-changing, something irrelevant.
This uncertainty wreaks havoc with our rapid perceptual categorisation system, causes stress, and leads to decision overload. Every email requires a decision! Do I respond to it? If so, now or later? How important is it? What will be the social, economic, or job-related consequences if I don’t answer, or if I don’t answer right now?
'Because it is limited in characters, texting discourages thoughtful discussion or any level of detail, and its addictive problems are compounded by its hyper-immediacy.'
Pinterest
‘Because it is limited in characters, texting discourages thoughtful discussion or any level of detail, and its addictive problems are compounded by its hyper-immediacy.’ Photograph: Alamy
Now of course email is approaching obsolescence as a communicative medium. Most people under the age of 30 think of email as an outdated mode of communication used only by “old people”. In its place they text, and some still post to Facebook. They attach documents, photos, videos, and links to their text messages and Facebook posts the way people over 30 do with email. Many people under 20 now see Facebook as a medium for the older generation.
For them, texting has become the primary mode of communication. It offers privacy that you don’t get with phone calls, and immediacy you don’t get with email. Crisis hotlines have begun accepting calls from at-risk youth via texting and it allows them two big advantages: they can deal with more than one person at a time, and they can pass the conversation on to an expert, if needed, without interrupting the conversation.
But texting suffers from most of the problems of email and then some. Because it is limited in characters, it discourages thoughtful discussion or any level of detail. And the addictive problems are compounded by texting’s hyperimmediacy. Emails take some time to work their way through the internet and they require that you take the step of explicitly opening them. Text messages magically appear on the screen of your phone and demand immediate attention from you. Add to that the social expectation that an unanswered text feels insulting to the sender, and you’ve got a recipe for addiction: you receive a text, and that activates your novelty centres. You respond and feel rewarded for having completed a task (even though that task was entirely unknown to you 15 seconds earlier). Each of those delivers a shot of dopamine as your limbic system cries out “More! More! Give me more!”
In a famous experiment, my McGill colleagues Peter Milner and James Olds, both neuroscientists, placed a small electrode in the brains of rats, in a small structure of the limbic system called the nucleus accumbens. This structure regulates dopamine production and is the region that “lights up” when gamblers win a bet, drug addicts take cocaine, or people have orgasms – Olds and Milner called it the pleasure centre. A lever in the cage allowed the rats to send a small electrical signal directly to their nucleus accumbens. Do you think they liked it? Boy how they did! They liked it so much that they did nothing else. They forgot all about eating and sleeping. Long after they were hungry, they ignored tasty food if they had a chance to press that little chrome bar; they even ignored the opportunity for sex. The rats just pressed the lever over and over again, until they died of starvation and exhaustion. Does that remind you of anything? A 30-year-old man died in Guangzhou (China) after playing video games continuously for three days. Another man died in Daegu (Korea) after playing video games almost continuously for 50 hours, stopped only by his going into cardiac arrest.
Each time we dispatch an email in one way or another, we feel a sense of accomplishment, and our brain gets a dollop of reward hormones telling us we accomplished something. Each time we check a Twitter feed or Facebook update, we encounter something novel and feel more connected socially (in a kind of weird, impersonal cyber way) and get another dollop of reward hormones. But remember, it is the dumb, novelty-seeking portion of the brain driving the limbic system that induces this feeling of pleasure, not the planning, scheduling, higher-level thought centres in the prefrontal cortex. Make no mistake: email-, Facebook- and Twitter-checking constitute a neural addiction.
© Daniel J. Levitin. Extracted from The Organized Mind: Thinking Straight in the Age of Information Overload, published by Viking (£20). Click here to buy it for £16.

Thursday 4 December 2014

Catalyst ABC Prograam Nov 2014



this fellow has some interesting comments to folllow up later

 

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The great scientist Prof Louis Kervran ( nominated for a nobel prize in 1975) made the comment in his book" Breads Biological Transmutations" Nutritionist' & Dieticians only touch the surface of the benefits of Carbohydrates to the human body, I break down every vitamin and mineral in grain and explain the benefits to the human body both inside and out
All participants on the Catalyst programme failed to mention what type of carbohydrate they were referring to and there is a vast difference. If they were referring to starch carbohydrates where the bran & germ have been removed from the grain ( called the imposter carb) and which represents 95% of all carbs sold, they were on the money.
If they were referring to complex ( complete) carbs, they couldn't have been further from the truth
Bread contains more nutrients per weight than meat, milk, potatoes, fruits, and vegetables (Thomas, 1976).

In its unrefined state bread could supply 800 calories and 30 grams of protein per person were it evenly distributed worldwide (Davis, 1981). This amount would also supply a 25 to 49 year old man with 30% of his energy requirements and 49% of his protein requirements (Health & Welfare, 1990).
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    Link for your quote
    http://eap.mcgill.ca/publications/EAP35.htm

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      Yes Mauricio and thank you, the link you posted is pretty compelling evidence on the benefits of Carbohydrates.

      When I eat my 100% freshly milled organic whole grain bread, made with 3 ingredients ( freshly milled organic grain, filtered water & Celtic salt) and based on the work of Louis Kervran, I know how good I feel and how this bread sustains me for long periods
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    I am confused by your reference to Kervran as he was a little published, barely recognised scientist who did some interesting work but was hardly 'great'.!
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      Jenny, I think you should do more research before commenting on Kervran he was a giant in science.
      Just because many of his books were written in French not English, doesn't mean to say he wasn't well published. He was and his list of books mentioned below are testament to that. In addition he had many papers published as well
      As well as being nominated for a Nobel prize here are some of his other credentials.He was far more informed on Carbohydrates than any of the professionals mentioned on the Catalyst programme
      Can I ask you, have you read any of his books, or used any of his transmutation methods yourself
      Kervran was born in Quimper, Finistère (Brittany). He had received a degree as a physics engineer in 1925.[2] In WWII he was part of the French Resistance. He was a member of the New York Academy of Sciences, Director of Conferences of the Paris University, Member of Conseil d'Hygiene de la Seine, a Member of the Commission du Conseil Supérieur de la Recherche Scientifique (1966). He was the recognised expert on radiation poisoning for the French government since 1945.
      Corentin Louis Kervran - Selected Works
      Selected Works
      Books

      •Transmutations Biologiques: Métabolismes Aberrants de l'Azote, le Potassium et le Magnésium (1962) Paris : Librairie Maloine S.A. (2nd ed. 1963, 3rd ed. 1965)
      •Transmutations naturelles non radioactives ; une propriete nouvelle de la matiere Paris : Librairie Maloine, (1963) OCLC 21388057
      •Transmutations à la faible énergie : synthèse et développements (1964) Paris : Maloine OCLC 35460556
      •A la découverte des transmutations biologiques : une explication des phénomènes biologiques aberrants (1966) Paris : Le Courrier du livre OCLC 30562980
      •Preuves Relatives à l'Existence des Transmutations Biologiques (1968) Paris : Librairie Maloine S.A.
      •Transmutations biologiques en agronomie (1970) Paris : Librairie Maloine S.A.
      •Preuves en géologie et physique de transmutations à faible énergie (1973) Paris : Maloine ISBN 2-224-00053-7 OCLC 914685
      •Preuves en biologie de transmutations à faible énergie (1975) Paris, Maloine, S.A. ISBN 2-224-00178-9 OCLC 1603879, (2nd edition, 1995).
      •Transmutations Biologique et Physique Moderne (1982) Paris : Librairie Maloine S.A.

      Books in English:
      •Biological Transmutations C. Louis Kervran, translation and adaptation by Michel Abehsera, 1989, 1998 (first published in 1972) ISBN 0-916508-47-1 OCLC 301517796 (extract of three of Kervran's books)
      •Biological transmutations, revised and edited by Herbert & Elizabeth Rosenauer, London, Crosby Lockwood 1972 (reprinted by Beekman, New York, in 1998 under ISBN 0-8464-0195-9)
      >> Reply
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how come they didn't interview peter siddle, who eats 20 bananas a day with no weight issues. why do you cherry pick the one cricketer (so 1 in 11??) that is on this diet. he also can't stop getting out lbw. maybe they are related?

jokes aside, they have fed you one half of the story. that's not to say low-carb diets might work, or be beneficial, but a show based on "science", should present a balanced arguement.

also, saturated fat is still bad for you

also, when Professor Noakes tells you that we don't need to carbohydrate because our liver produces it, then, by his logic, our diet only need to consist of the 6 essential amino acids, and 2 essential fatty acids (which aren't saturated fats by the way). hardly a logical argument, but who needs facts when you want to be famous