gut flora

antibiotics destroy got microflora
starch is need for Klebia for arthritis

Bones

the telepgragh article
the best iherb equivalent

and here is the telie description
Judith Brodie, chief executive of Arthritis Care, said: “Many people with osteoarthritis live for years in great pain before eventually needing joint replacements. This is the first study to show benefit from strontium ranelate so it is early days, but if there is a treatment which can hold back the disease, delay knee replacements and help people to live more active lives for longer, then it will be good news for the millions of people in the UK with this debilitating condition.” 

seaweed bread 

Sleep Experiment 01

Date March 23rd, 2012

Goal :  Improve  Certain Brain Factors:  Start with

1. Melatonin, Cortisol , Autophagy, 
2. Circadian Clock reset and resilience, 
3. up-regulate good receptors, down-regulate "bad receptors"
4. plus unknown
5. telomere length
6. general brain volume, rewiring through neuro-plasticity and health

hypothesis development:

1.  that sleep is a medicine
2. that sleep is a free medicine
3. that perfect sleep is a free potent secret medicine
4. that perfect sleep is a free potent secret medicine as it permits restoration of ancient neuron behavior to an optimal set point where circadian cycle of dark-light worked in ancient times when there was no artificial light pollution and EMF pollution.  we go back to blue green algae, and consider the genetic links to humans

1. background:
2. resources
3. computer colour  http://stereopsis.com/flux/
4. room lights

Materials and methods : 

Pre sleep, 

1. starts at dusk
2. apply http://stereopsis.com/flux/ to computer to match spectral light from screen to night
3. switch on night lighting
4. prepare for sleep at 1030pm: checklist

sleep phase: no blue light, no photons if possible, cool temperature

1. bed at 1100pm
2. exogenous supports : checklist
3. Jelly lamp for winddown
4. Hibermate eye shield
5. bathroom light yellow
6. jelly wash lamp for wake up

awake phase : measure and note

1. results:
2. measure wake up time
3. measure feeling
4. measure skin, tiredness of eyes
5. measure cortisol during day , saliva
6. measure temperature
7. measure pulse rate
8. record fast time
9. Discussion:
10. COnclusion

Sleep March 15th

low blue light yellow light
green Light
Light and Depression
Vitamin A and Hypothalamus
Green Light on Hat for eyes
Tubing for cooling
hormones 1968 ANtartica
Cnacer and ANtartica personal
twilight lamp and radio
Grey Hair Starting point
Matress
Free Software to change screen colour duirng the day
JD MOYER blog
Leangains
Jellyfish wake up light from australia

Cold Resources

Skin thermometer_01
Skin Thermometer_02
csiro_telomere length
reach_lab_adelaide
vegan B12 nsw
green light canada
depression and electrical stimualtion
yellow glasses yellow lights
Gut Clock
Ageing Ben Best
Brightgreen LED
FAn 12VDC

March 2012 Seeds

Dive Reflex
Ray Cronise
light and sleep 2007
Canadian Light Therapy
3D MRI software MAC
sleep mask aussie
Havard Sleep Paper 01
Annie evans be who you wnat to be
neem Uses
skip danger

Big Questions

1. is there a  best angle to avoid exogenous hormone therapy? maybe, test
2. if mainstream does not have the answers, where do i start? Look at the everyday as a mystery.
3. sleep
4. the gut

NY TIMES_ Blue Light 2012

 http://www.nytimes.com/2012/02/21/health/aging-of-eyes-is-blamed-in-circadian-rhythm-disturbances.html?_r=1

http://www.nytimes.com/2012/02/21/health/aging-of-eyes-is-blamed-in-circadian-rhythm-disturbances.html?_r=1 

 

 

Aging of Eyes Is Blamed for Range of Health Woes

By LAURIE TARKAN

Published: February 20, 2012

THE HYPOTHESIS

Enlarge This Image

Ellen Weinstein

The aging eye filters out blue light, affecting circadian rhythm and health in older adults.

THE INVESTIGATORS

Dr. Martin Mainster and Dr. Patricia Turner, University of Kansas School of Medicine.

For decades, scientists have looked for explanations as to why certain conditions occur with age, among them memory loss, slower reaction time, insomnia and even depression. They have scrupulously investigated such suspects as high cholesterol, obesity, heart disease and an inactive lifestyle.

Now a fascinating body of research supports a largely unrecognized culprit: the aging of the eye.

The gradual yellowing of the lens and the narrowing of the pupil that occur with age disturb the body’s circadian rhythm, contributing to a range of health problems, these studies suggest. As the eyes age, less and less sunlight gets through the lens to reach key cells in the retina that regulate the body’s circadian rhythm, its internal clock.

“We believe the effect is huge and that it’s just beginning to be recognized as a problem,” said Dr. Patricia Turner, an ophthalmologist in Leawood, Kan., who with her husband, Dr. Martin Mainster, a professor of ophthalmology at the University of Kansas Medical School, has written extensively about the effects of the aging eye on health.

Circadian rhythms are the cyclical hormonal and physiological processes that rally the body in the morning to tackle the day’s demands and slow it down at night, allowing the body to rest and repair. This internal clock relies on light to function properly, and studies have found that people whose circadian rhythms are out of sync, like shift workers, are at greater risk for a number of ailments, including insomnia, heart disease and cancer.

“Evolution has built this beautiful timekeeping mechanism, but the clock is not absolutely perfect and needs to be nudged every day,” said Dr. David Berson, whose lab at Brown University studies how the eye communicates with the brain.

So-called photoreceptive cells in the retina absorb sunlight and transmit messages to a part of the brain called the suprachiasmatic nucleus (S.C.N.), which governs the internal clock. The S.C.N. adjusts the body to the environment by initiating the release of the hormone melatonin in the evening and cortisol in the morning.

Melatonin is thought to have many health-promoting functions, and studies have shown that people with low melatonin secretion, a marker for a dysfunctional S.C.N., have a higher incidence of many illnesses, including cancer, diabetes and heart disease.

It was not until 2002 that the eye’s role in synchronizing the circadian rhythm became clear. It was always believed that the well-known rods and cones, which provide conscious vision, were the eye’s only photoreceptors. But Dr. Berson’s team discovered that cells in the inner retina, called retinal ganglion cells, also had photoreceptors and that these cells communicated more directly with the brain.

These vital cells, it turns out, are especially responsive to the blue part of the light spectrum. Among other implications, that discovery has raised questions about our exposure to energy-efficient light bulbs and electronic gadgets, which largely emit blue light.

But blue light also is the part of the spectrum filtered by the eye’s aging lens. In a study published in The British Journal of Ophthalmology, Dr. Mainster and Dr. Turner estimated that by age 45, the photoreceptors of the average adult receive just 50 percent of the light needed to fully stimulate the circadian system. By age 55, it dips to 37 percent, and by age 75, to a mere 17 percent.

“Anything that affects the intensity of light or the wavelength can have important consequences for the synchronization of the circadian rhythm, and that can have effects on all types of physiological processes,” Dr. Berson said.

Several studies, most in European countries, have shown that the effects are not just theoretical. One study, published in the journal Experimental Gerontology, compared how quickly exposure to bright light suppresses melatonin in women in their 20s versus in women in their 50s. The amount of blue light that significantly suppressed melatonin in the younger women had absolutely no effect on melatonin in the older women. “What that shows us is that the same amount of light that makes a young person sit up in the morning, feel awake, have better memory retention and be in a better mood has no effect on older people,” Dr. Turner said.

Another study, published in The Journal of Biological Rhythms, found that after exposure to blue light, younger subjects had increased alertness, decreased sleepiness and improved mood, whereas older subjects felt none of these effects.

Researchers in Sweden studied patients who had cataract surgery to remove their clouded lenses and implant clear intraocular lenses. They found that the incidence of insomnia and daytime sleepiness was significantly reduced. Another study found improved reaction time after cataract surgery.

“We believe that it will eventually be shown that cataract surgery results in higher levels of melatonin, and those people will be less likely to have health problems like cancer and heart disease,” Dr. Turner said.

That is why Dr. Mainster and Dr. Turner question a practice common in cataract surgery. About one-third of the intraocular lenses implanted worldwide are blue-blocking lenses, intended to reduce the risk of macular degeneration by limiting exposure to potentially damaging light.

But there is no good evidence showing that people who have cataract surgery are at greater risk of macular degeneration. And evidence of the body’s need for blue light is increasing, some experts say.

“You can always wear sunglasses if you’re in a brilliant environment that’s uncomfortable. You can remove those sunglasses for optimal circadian function, but you can’t take out the filters if they’re permanently implanted in your eyes,” Dr. Mainster said.

Because of these light-filtering changes, Dr. Mainster and Dr. Turner believe that with age, people should make an effort to expose themselves to bright sunlight or bright indoor lighting when they cannot get outdoors. Older adults are at particular risk, because they spend more time indoors.

“In modern society, most of the time we live in a controlled environment under artificial lights, which are 1,000 to 10,000 times dimmer than sunlight and the wrong part of the spectrum,” Dr. Turner said.

In their own offices, Dr. Mainster and Dr. Turner have installed skylights and extra fluorescent lights to help offset the aging of their own eyes.

Diving reflex

following Kruse,
started here
then this descriptioon of diving reflex use in breathing
the wiki view of diving reflex
some background